This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hederstedt, B Articles by Norberg, R Search for Related Content PubMed PubMed Citation Articles by Hederstedt, B Articles by Norberg, R

 Previous Article  |  Next Article 

J Clin Microbiol. 1980 June; 11(6): 720-723

Extremely high titers of serum antibodies against the streptococcal exoenzyme deoxyribonuclease B.

ABSTRACT

In sera from 4 of 25,000 individuals tested for antibodies against streptococci, extremely high antideoxyribonuclease B titers ( > 10(6) U/ml) were found. Two of the cases were diagnosed as monoclonal gammopathies. The M-components were shown to possess the anti-deoxyribonuclease B activity. The other two cases were diagnosed as relapsing erysipelas. The high serum titers of deoxyribonuclease B antibodies were accompanied by a very inflammatory reactivity in the patients' sera and by an oligopolyclonal pattern of immunoglobulin G. In routine diagnoses of streptococcal infections with the anti-deoxyribonuclease B test, patients with extremely high serum titers should be examined for the possible occurrence of gammopathies.

This article has been cited by other articles:

• Eriksson, A., Eriksson, B., Holm, S. E., Norgren, M. (1999). Streptococcal DNase B Is Immunologically Identical to Superantigen SpeF but Involves Separate Domains. CVI 6: 133-136 [Abstract] [Full Text]