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Journal of Clinical Microbiology, January 1998, p. 305-308, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Results from 5 Years of Nationwide DNA Fingerprinting of Mycobacterium tuberculosis Complex Isolates in a Country with a Low Incidence of M. tuberculosis Infection

Jeanett Bauer,1,* Zhenhua Yang,1 Sigrid Poulsen,2 and Åse B. Andersen1

Departments of Mycobacteriology1 and Epidemiology,2 Statens Serum Institut, 2300 Copenhagen S, Denmark

Received 20 June 1997/Returned for modification 29 July 1997/Accepted 21 October 1997

Results from DNA fingerprint analyses of Mycobacterium tuberculosis complex isolates from tuberculosis (TB) patients diagnosed during 5 years in Denmark are presented. The lack of success in eradicating TB in this low-incidence country may be explained by an unrecognized high frequency of active TB transmission (57%) among native Danes. Only two strains of M. tuberculosis are responsible for 40% of all clustered cases of TB among Danes.

* Corresponding author. Mailing address: Department of Mycobacteriology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark. Phone: 45 3268 3705. Fax: 45 3268 3871. E-mail: jba{at}ssi.dk.

Journal of Clinical Microbiology, January 1998, p. 305-308, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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