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Journal of Clinical Microbiology, May 2002, p. 1818-1820, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1818-1820.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Performance Characteristics of VIDAS and Directigen Respiratory Syncytial Virus (RSV) Antigen Detection Assays and Culture for the Identification of RSV in Respiratory Specimens

Julie A. Ribes,1* John Pat Seabolt,2 and Sue B. Overman2

Department of Pathology and Laboratory Medicine,1 University of Kentucky Hospital, University of Kentucky, Lexington, Kentucky 40536-02932

Received 6 November 2001/ Returned for modification 28 November 2001/ Accepted 10 February 2002

In a comparison of the Directigen and VIDAS respiratory syncytial virus antigen detection assays with viral culture, the sensitivity, specificity, positive and negative predictive values, and testing efficiency were 86, 93.1, 82.7, 94.6, and 91.2% for Directigen; 96.1, 90.8, 80.3, 98.3, and 92.3% for VIDAS; and 88.2, 100, 100, 95.7, and 96.8% for viral culture, respectively.

* Corresponding author. Mailing address: University of Kentucky, Department of Pathology and Laboratory Medicine, MS-117 Medical Center, 800 Rose St., Lexington, KY 40536-0298. Phone: (859) 323-1368. Fax: (859) 323-5054. E-mail: jaribes{at}uky.edu.

Journal of Clinical Microbiology, May 2002, p. 1818-1820, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1818-1820.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2002 by the American Society for Microbiology. All rights reserved.