JCM Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Richardson, M.
Right arrow Articles by van Helden, P. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Richardson, M.
Right arrow Articles by van Helden, P. D.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, August 2002, p. 2750-2754, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.2750-2754.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Multiple Mycobacterium tuberculosis Strains in Early Cultures from Patients in a High-Incidence Community Setting

Madalene Richardson,1 Nora M. Carroll,1 Erica Engelke,1 Gian D. van der Spuy,1 Faeeza Salker,2 Zahn Munch,2 Robert P. Gie,2 Robin M. Warren,1 Nulda Beyers,2 and Paul D. van Helden1*

MRC Centre for Molecular and Cellular Biology, Department of Medical Biochemistry,1 Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa2

Received 26 February 2002/ Returned for modification 21 April 2002/ Accepted 4 May 2002

In an ongoing molecular epidemiology study, human immunodeficiency virus-negative patients with first-time pulmonary tuberculosis from a high-incidence community were enrolled. Mycobacterium tuberculosis strains were identified by restriction fragment length polymorphism analysis with two fingerprinting probes. Of 131 patients, 3 (2.3%) were shown to have a mixture of strains in one or two of their serial cultures. This study further investigated these cases with disease caused by multiple M. tuberculosis strains in the context of the molecular epidemiology of the study setting.

* Corresponding author. Mailing address: P.O. Box 19063, Tygerberg 7505, South Africa. Phone: 27 21 9389401. Fax: 27 21 9389476. E-mail: pvh{at}sun.ac.za.

Journal of Clinical Microbiology, August 2002, p. 2750-2754, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.2750-2754.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2002 by the American Society for Microbiology. All rights reserved.