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Journal of Clinical Microbiology, October 2003, p. 4790-4792, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4790-4792.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Assessment of Immunoglobulin M Enzyme Immunoassays for Diagnosis of Measles

Graham A. Tipples,1* Rasool Hamkar,2 Talat Mohktari-Azad,2 Michael Gray,1 Geoff Parkyn,1 Carol Head,3 and Samuel Ratnam3

National Microbiology Laboratory, Health Canada, Winnipeg, Manitoba,1 Newfoundland Public Health Laboratory, St. John's, Newfoundland, Canada,3 Tehran University of Medical Sciences, Tehran, Iran2

Received 21 March 2003/ Returned for modification 21 May 2003/ Accepted 16 July 2003

We evaluated the performance of three commercial measles immunoglobulin M enzyme immunoassays from Meddens, Denka Seiken, and Behring. The sensitivities were determined to be 96.7% for the Meddens and Denka Seiken assays and 87.9% for the Behring assay. The specificities of the assays were determined to be 94.6% for Meddens, 98.2% for Denka Seiken, and 98.7% for Behring.

* Corresponding author. Mailing address: National Microbiology Laboratory, Health Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada R3E 3R2. Phone: (204) 789-6080. Fax: (204) 789-5009. E-mail: graham_tipples{at}hc-sc.gc.ca.

Journal of Clinical Microbiology, October 2003, p. 4790-4792, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4790-4792.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2003 by the American Society for Microbiology. All rights reserved.