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Journal of Clinical Microbiology, October 2003, p. 4862-4864, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4862-4864.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

High Disease Burden of Diarrhea Due to Enterotoxigenic Escherichia coli among Rural Egyptian Infants and Young Children

Malla R. Rao,1,{dagger}* Remon Abu-Elyazeed,2,{ddagger} Stephen J. Savarino,2,3 Abdollah B. Naficy,1,{dagger} Thomas F. Wierzba,2 Ibrahim Abdel-Messih,2 Hind Shaheen,2 Robert W. Frenck Jr.,2 Ann-Mari Svennerholm,4 and John D. Clemens1,5

Epidemiology Branch, National Institute of Child Health and Human Development, Bethesda,1 Naval Medical Research Center, Silver Spring, Maryland,3 U.S. Naval Medical Research Unit No. 3, Cairo, Egypt,2 Department of Medical Microbiology and Immunology, University of Göteborg, Göteborg, Sweden,4 International Vaccine Institute, Seoul, South Korea5

Received 3 June 2003/ Returned for modification 8 July 2003/ Accepted 29 July 2003

The incidence of enterotoxigenic Escherichia coli diarrhea among Egyptian children was 1.5 episodes per child per year and accounted for 66% of all first episodes of diarrhea after birth. The incidence increased from 1.7 episodes per child per year in the first 6 months of life to 2.3 in the second 6 months and declined thereafter.

* Corresponding author. Mailing address: PIPB, NIAID, NIH, 6610 Rockledge Dr., Room 5044, Bethesda, MD 20892. Phone: (301) 451-3749. Fax: (301) 402-0659. E-mail: mr8u{at}nih.gov.

{dagger} Present address: NIAID, NIH, Bethesda, Md.

{ddagger} Present address: GlaxoSmithKline Biologicals, Singapore.

Journal of Clinical Microbiology, October 2003, p. 4862-4864, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4862-4864.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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