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Journal of Clinical Microbiology, May 2004, p. 2271-2274, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2271-2274.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Asymptomatic and Symptomatic Excretion of Noroviruses during a Hospital Outbreak of Gastroenteritis

Chris I. Gallimore,1* David Cubitt,2 Nelita du Plessis,1 and Jim J. Gray1

Enteric, Respiratory and Neurological Virus Laboratory Central Public Health Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, Colindale, London, NW9 5HT,1 Department of Virology, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children, London, WC1N 3JH, United Kingdom2

Received 11 September 2003/ Returned for modification 23 January 2004/ Accepted 11 February 2004

During an investigation of a hospital outbreak of norovirus gastroenteritis identified as being caused by a recombinant genogroup II (rGII-3a) strain, fecal specimens collected from asymptomatic staff and patients were tested by nested PCR. A GII-4 norovirus strain, the predominant strain associated with outbreaks in hospitals over the last few years, was detected in 26 and 33% of asymptomatic staff and patients, respectively. No rGII-3a (Harrow/Mexico) norovirus strains were detected in the samples of asymptomatic staff or patients.

* Corresponding author. Mailing address: Enteric, Respiratory and Neurological Virus Laboratory, Central Public Health Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Ave., Colindale, London, NW9 5HT, United Kingdom. Phone: 44-208-200-4400. Fax: 44-208-205-8195. E-mail: christopher.gallimore{at}hpa.org.uk.

Journal of Clinical Microbiology, May 2004, p. 2271-2274, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2271-2274.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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Copyright © 2004 by the American Society for Microbiology. All rights reserved.