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Journal of Clinical Microbiology, April 2008, p. 1494-1497, Vol. 46, No. 4
0095-1137/08/$08.00+0     doi:10.1128/JCM.01945-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Assessment of Rapid Tests for Detection of Human Immunodeficiency Virus-Specific Antibodies in Recently Infected Individuals{triangledown}

Brian Louie,1* Ernest Wong,1 Jeffrey D. Klausner,1,2 Sally Liska,1 Frederick Hecht,2 Terri Dowling,1 Martha Obeso,1 Susan S. Phillips,1 and Mark W. Pandori1

San Francisco Department of Public Health, San Francisco, California,1 University of California, San Francisco, San Francisco, California2

Received 2 October 2007/ Returned for modification 11 January 2008/ Accepted 22 January 2008

We have evaluated four current Food and Drug Administration-cleared rapid tests for human immunodeficiency virus (HIV)-specific antibodies with a panel of specimens from recently infected individuals. Recent infection was detected by RNA-based screening coupled with enzyme immunoassay-based testing. We found that the sensitivities of the various rapid tests vary greatly with regard to their ability to detect HIV-specific antibodies in recently infected individuals.

* Corresponding author. Mailing address: San Francisco Department of Public Health, 101 Grove St., Room 412, San Francisco, CA 94102. Phone: (415) 554-2800. Fax: (415) 431-0651. E-mail: brian.louie{at}sfdph.org

{triangledown} Published ahead of print on 30 January 2008.

Journal of Clinical Microbiology, April 2008, p. 1494-1497, Vol. 46, No. 4
0095-1137/08/$08.00+0     doi:10.1128/JCM.01945-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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