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J Clin Microbiol. 1978 September; 8(3): 277-282

Solid-phase enzyme-linked immunosorbent assay for detection of hepatitis A virus.

S A Locarnini, S M Garland, N I Lehmann, R C Pringle and I D Gust

ABSTRACT

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of hepatitis A virus in human fecal specimens. Investigations with 88 fecal specimens from 77 patients with suspected viral hepatitis and 8 of their household contacts showed that ELISA was as specific and sensitive as radioimmunoassay and almost as sensitive as immune electron microscopy. The ELISA is quick and simple to perform, does not require sophisticated technical equipment, and can be read with the naked eye, making it suitable for field work and rapid diagnosis.

J Clin Microbiol. 1978 September; 8(3): 277-282






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1978 by the American Society for Microbiology. All rights reserved.