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J. Clin. Microbiol. doi:10.1128/JCM.01057-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Molecular analysis of varicella-zoster virus (VZV) strains circulating in Tanzania demonstrates the presence of VZV genotype M1

Bernhard-Nocht-Institute for Tropical Medicine, Diagnostic Virology Laboratory, D-20359 Hamburg, Germany; Ikonda Hospital, Makete district, Tanzania; Institute of Medical Virology, Hospital of the Johann Wolfgang Goethe University, D-60596 Frankfurt am Main, Germany; Department of Dermatology and Venereology, University of Rostock, D-18055 Rostock, Germany; Computational and Molecular Population Genetics Laboratory, Zoological Institute, University of Bern, CH-3012 Bern, Switzerland; Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute for Novel and Emerging Infectious Diseases, D-17493 Greifswald, Germany

^* To whom correspondence should be addressed. Email: jonassi{at}gmx.de.

	Abstract

Based on analysis of 16,392 base pairs encompassing the complete open reading frames (ORFs) 1, 5, 31, 36, 37, 47, 60, 62, 67, and 68 of the varicella-zoster virus (VZV) genome VZV genotype M1 was found in swab samples originating from 8 Tanzanian zoster patients. Moreover, sequence analysis suggests recombination events between different VZV genotypes within the ORFs 1, 31, 60 and 67.